Laurence Kraus-Berthier Selected Research

S55746

1/2019	Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia.
4/2018	S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.

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Laurence Kraus-Berthier Research Topics

Disease

10	Neoplasms (Cancer) 01/2019 - 08/2002
3	Leukemia 01/2019 - 08/2002
3	Carcinoma (Carcinomatosis) 01/2005 - 08/2002
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2019 - 04/2018
2	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 04/2018 - 04/2016
2	Poisoning 08/2007 - 02/2004
2	Leukemia P388 01/2005 - 04/2004
1	Multiple Myeloma 01/2020
1	Philadelphia Chromosome 01/2020
1	Carcinogenesis 12/2018
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 04/2018
1	Lymphoma (Lymphomas) 04/2016
1	Neoplasm Metastasis (Metastasis) 01/2014
1	Uveal melanoma 01/2014
1	Nasopharyngeal Carcinoma 01/2014
1	Breast Neoplasms (Breast Cancer) 12/2013
1	Adenocarcinoma 03/2009
1	Colonic Neoplasms (Colon Cancer) 03/2004
1	Lewis Lung Carcinoma 08/2002

Drug/Important Bio-Agent (IBA)

4	Pharmaceutical PreparationsIBA 01/2019 - 08/2002
3	abexinostatIBA 04/2016 - 12/2013
3	Histone Deacetylase InhibitorsIBA 04/2016 - 12/2013
2	S63845IBA 01/2020 - 01/2019
2	venetoclaxIBA 01/2020 - 04/2018
2	S55746IBA 01/2019 - 04/2018
2	1,2,3,4-tetrahydroisoquinolineIBA 01/2019 - 12/2018
2	Biomarkers (Surrogate Marker)IBA 12/2018 - 12/2013
2	DNA (Deoxyribonucleic Acid)IBA 08/2007 - 02/2004
1	Tyrosine Kinase InhibitorsIBA 01/2020
1	blinatumomabIBA 01/2020
1	Chimeric Antigen ReceptorsIBA 01/2020
1	CaspasesIBA 12/2018
1	Apoptosis Regulatory ProteinsIBA 04/2018
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 04/2016
1	Cyclin D1IBA 04/2016
1	ChromatinIBA 04/2016
1	Epstein-Barr virus encoded RNA 1IBA 01/2014
1	Biological ProductsIBA 01/2014
1	Proteins (Proteins, Gene)FDA Link 01/2014
1	Viral RNAIBA 01/2014
1	Untranslated RNA (Noncoding RNA)IBA 01/2014
1	S 23906-1IBA 03/2009
1	Histones (Histone)IBA 08/2007
1	PoisonsIBA 01/2005
1	4'-demethylepipodophyllotoxinIBA 01/2005
1	Antineoplastic Agents (Antineoplastics)IBA 01/2005
1	Etoposide (VP 16)FDA LinkGeneric 01/2005
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 01/2005
1	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2004
1	indenoindoleIBA 11/2004
1	SulfonamidesIBA 04/2004
1	MorpholinosIBA 04/2004
1	Acronine (Acronycine)IBA 03/2004
1	S30972-1IBA 08/2002
1	S 16020-2IBA 08/2002

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 01/2019 - 01/2005
2	Therapeutics 01/2014 - 12/2013
1	Radiotherapy 01/2014